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English
TP53 forms homotetramers
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-6804762)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
part of
Regulation of TP53 Expression
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
exact match
https://identifiers.org/reactome:R-HSA-6804762
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
has part(s)
tumor protein p53
quantity
4
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
TP53 Tetramer [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
cites work
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
p53 oligomerization and DNA looping are linked with transcriptional activation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
Interaction of p53 with its consensus DNA-binding site
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
Identifiers
Reactome ID
R-HSA-6804762
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6804762
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