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(Q50290335)
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USP7 deubiquitinates TP53 and counteracts MDM2
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-3215310)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
part of
Regulation of TP53 Degradation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
exact match
https://identifiers.org/reactome:R-HSA-3215310
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
has part(s)
water
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
PolyUb-TP53 Tetramer [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
TP53 Tetramer [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
Ub [nucleoplasm]
quantity
4
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
Ubiquitin specific peptidase 7
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
cites work
Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
Molecular recognition of p53 and MDM2 by USP7/HAUSP
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
A dynamic role of HAUSP in the p53-Mdm2 pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
Identifiers
Reactome ID
R-HSA-3215310
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3215310
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