(Q50291705)

English

IKBKB phosphorylates TPL2 (MAP3K8) at Ser400

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5684275)

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Statements

biological process

1 reference

8 July 2022

MAP3K8 (TPL2)-dependent MAPK1/3 activation

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5684275

1 reference

8 July 2022

1

object has role

1 reference

8 July 2022

NFKB1:MAP3K8:TNIP2 [cytosol]

1

object has role

1 reference

8 July 2022

1

object has role

1 reference

8 July 2022

NFKB1:p-S400-MAP3K8:TNIP2 [cytosol]

1

object has role

1 reference

8 July 2022

p-S177,S181-IKKB:IKKA:NEMO [cytosol]

1

object has role

1 reference

8 July 2022

IκB kinase 2 regulates TPL-2 activation of extracellular signal-regulated kinases 1 and 2 by direct phosphorylation of TPL-2 serine 400

1 reference

8 July 2022

IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2.

1 reference

8 July 2022

Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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