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(Q50291710)
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English
SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5684250)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
part of
MAP3K8 (TPL2)-dependent MAPK1/3 activation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
exact match
https://identifiers.org/reactome:R-HSA-5684250
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
has part(s)
SCF-beta-TrCP1,2:p-S927,S932-NFKB1:p-S,T-MAP3K8:TNIP2 [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
(BTRC:CUL1:SKP1),(FBXW11:CUL1:SKP1) [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
3xUb, 2xp-S-NFKB1(1-968):p-S,T-MAP3K8:TNIP2 [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
SCF-beta-TrCP1,2:p-S927,S932-NFKB1:p-S,T-MAP3K8:TNIP2 [cytosol]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
Ub [cytosol]
quantity
9
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
cites work
Enzymes catalyzing ubiquitination and proteolytic processing of the p105 precursor of nuclear factor kappaB1.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
Identifiers
Reactome ID
R-HSA-5684250
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5684250
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