(Q50291742)

English

K63-linked ubiquitination of RIP1 bound to the activated TLR complex

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9014342)

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Statements

biological process

1 reference

8 July 2022

TICAM1, RIP1-mediated IKK complex recruitment

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9014342

1 reference

8 July 2022

viral dsRNA:TLR3:TICAM1:RIPK1 [endosome membrane]

1

object has role

1 reference

8 July 2022

activated TLR3:TICAM1:K63pUb-RIP1 [endosome membrane]

1

object has role

1 reference

8 July 2022

RIP1 ubiqutin ligases [cytosol]

1

object has role

1 reference

8 July 2022

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

1 reference

8 July 2022

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

1 reference

8 July 2022

cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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