(Q50291753)

English

Activation of recruited TAK1 within the activated TLR3 complex

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-177692)

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8 July 2022

TICAM1,TRAF6-dependent induction of TAK1 complex

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-177692

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8 July 2022

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8 July 2022

viral dsRNA:TLR3:TRIF:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [endosome membrane]

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8 July 2022

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8 July 2022

viral dsRNA:TLR3:TRIF:pUb-TRAF6:TAB1:TAB2,TAB3:free polyUb: p-TAK1 [endosome membrane]

1

1 reference

8 July 2022

viral dsRNA:TLR3:TRIF:polyUb-TRAF6:TAK1:TAB1:TAB2/TAB3: free polyUb chain [endosome membrane]

1

1 reference

8 July 2022

Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR

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8 July 2022

Ubiquitin-mediated activation of TAK1 and IKK.

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8 July 2022

TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

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8 July 2022

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

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8 July 2022

Essential function for the kinase TAK1 in innate and adaptive immune responses.

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q50291753)

Activation of recruited TAK1 within the activated TLR3 complex

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