(Q50291851)

English

HMGB1 binds LPS

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-6804100)

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Statements

biological process

1 reference

8 July 2022

Regulation of TLR by endogenous ligand

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-6804100

1 reference

8 July 2022

HC23,45-HMGB1 [extracellular region]

1

object has role

1 reference

8 July 2022

lipopolysaccharide

1

object has role

1 reference

8 July 2022

HC23,45-HMGB1:LPS [extracellular region]

1

object has role

1 reference

8 July 2022

HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

1 reference

8 July 2022

High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts.

1 reference

8 July 2022

High mobility group box 1 protein binding to lipopolysaccharide facilitates transfer of lipopolysaccharide to CD14 and enhances lipopolysaccharide-mediated TNF-alpha production in human monocytes.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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