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SFTPA/SFTPD binds TLR4:LY96
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5432852)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
part of
Regulation of TLR by endogenous ligand
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
exact match
https://identifiers.org/reactome:R-HSA-5432852
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
has part(s)
SFTPA oligomer, SFTPD oligomer [extracellular region]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
TLR4:LY96 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
SP-A/SP-D:TLR4:MD2 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
cites work
Surfactant protein A directly interacts with TLR4 and MD-2 and regulates inflammatory cellular response. Importance of supratrimeric oligomerization
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
Human pulmonary surfactant protein D binds the extracellular domains of Toll-like receptors 2 and 4 through the carbohydrate recognition domain by a mechanism different from its binding to phosphatidylinositol and lipopolysaccharide
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
Surfactant proteins SP-A and SP-D: structure, function and receptors.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
Pulmonary surfactant protein D inhibits lipopolysaccharide (LPS)-induced inflammatory cell responses by altering LPS binding to its receptors.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
Identifiers
Reactome ID
R-HSA-5432852
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5432852
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