(Q50291855)

English

SFTPA/SFTPD binds TLR2:TLR1

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5432814)

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Statements

biological process

1 reference

8 July 2022

Regulation of TLR by endogenous ligand

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5432814

1 reference

8 July 2022

SFTPA oligomer, SFTPD oligomer [extracellular region]

1

object has role

1 reference

8 July 2022

TLR1:TLR2 [plasma membrane]

1

object has role

1 reference

8 July 2022

SFTPA/SFTPD:TLR2:TLR1 [plasma membrane]

1

object has role

1 reference

8 July 2022

Surfactant protein A inhibits peptidoglycan-induced tumor necrosis factor-alpha secretion in U937 cells and alveolar macrophages by direct interaction with toll-like receptor 2.

1 reference

8 July 2022

Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha secretion are down-regulated by lung collectin surfactant protein A.

1 reference

8 July 2022

Human pulmonary surfactant protein D binds the extracellular domains of Toll-like receptors 2 and 4 through the carbohydrate recognition domain by a mechanism different from its binding to phosphatidylinositol and lipopolysaccharide

1 reference

8 July 2022

Surfactant proteins SP-A and SP-D: structure, function and receptors.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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