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Gab2 binds the p85 subunit of Class 1A PI3 kinases
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-508247)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-508247
part of
Interleukin receptor SHC signaling
1 reference
stated in
Reactome
retrieved
13 July 2022
Reactome ID
R-HSA-508247
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-508247
exact match
https://identifiers.org/reactome:R-HSA-508247
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-508247
has part(s)
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-508247
p85-containing Class 1A PI3Ks [cytosol]
quantity
4
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-508247
Interleukin receptor complexes with activated Shc:GRB2:p-GAB2:p85-containing Class 1 PI3Ks [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-508247
cites work
Engagement of Gab1 and Gab2 in erythropoietin signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-508247
Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-508247
Identifiers
Reactome ID
R-HSA-508247
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-508247
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