(Q50293670)

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Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5690043)

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acyl-CoA metabolic process

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Mitochondrial Fatty Acid Beta-Oxidation

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https://identifiers.org/reactome:R-HSA-5690043

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MCFA-CoA, LCFA-CoA [cytosol]

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Cytosolic ACOTs, THEM4 [cytosol]

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Phosphatidylcholine transfer protein

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Structural Basis for Regulation of the Human Acetyl-CoA Thioesterase 12 and Interactions with the Steroidogenic Acute Regulatory Protein-related Lipid Transfer (START) Domain

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Phosphatidylcholine transfer protein interacts with thioesterase superfamily member 2 to attenuate insulin signaling

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The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism

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The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis

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Thioesterase superfamily member 2 (Them2) and phosphatidylcholine transfer protein (PC-TP) interact to promote fatty acid oxidation and control glucose utilization

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Functional and structural properties of mammalian acyl-coenzyme A thioesterases

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Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs

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PC-TP/StARD2: Of membranes and metabolism

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Crystal structure of human thioesterase superfamily member 2

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New players on the metabolic stage: How do you like Them Acots?

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Identification of fatty acid oxidation disorder patients with lowered acyl-CoA thioesterase activity in human skin fibroblasts

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A functional variant in the transcriptional regulatory region of gene LOC344967 cosegregates with disease phenotype in familial nasopharyngeal carcinoma.

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BFIT, a unique acyl-CoA thioesterase induced in thermogenic brown adipose tissue: cloning, organization of the human gene and assessment of a potential link to obesity

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Identifiers

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8 July 2022

(Q50293670)

Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA

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