(Q50294352)

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Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-400092)

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8 July 2022

Adrenaline,noradrenaline inhibits insulin secretion

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-400092

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8 July 2022

G-alpha(i,o):GDP:G beta:G gamma [plasma membrane]

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8 July 2022

G-alpha(i,o):GTP:G-beta:G-gamma [plasma membrane]

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8 July 2022

ADRA2A,C:ADR,NAd [plasma membrane]

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8 July 2022

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8 July 2022

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8 July 2022

Subtype-specific stimulation of [35S]GTPgammaS binding by recombinant alpha2-adrenoceptors

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8 July 2022

Inhibition of insulin secretion via distinct signaling pathways in alpha2-adrenoceptor knockout mice

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8 July 2022

Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors

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8 July 2022

Functional interactions of recombinant alpha 2 adrenergic receptor subtypes and G proteins in reconstituted phospholipid vesicles

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8 July 2022

Coupling of the alpha 2-adrenergic receptor to the inhibitory G-protein Gi and adenylate cyclase in HT29 cells

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8 July 2022

Two peptides from the alpha 2A-adrenergic receptor alter receptor G protein coupling by distinct mechanisms

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8 July 2022

Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits

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8 July 2022

Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel

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8 July 2022

Mechanisms of inhibition of insulin release

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8 July 2022

Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells

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8 July 2022

G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes.

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8 July 2022

Chimeric mutagenesis of putative G-protein coupling domains of the alpha2A-adrenergic receptor. Localization of two redundant and fully competent gi coupling domains

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q50294352)

Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins

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