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CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-211910)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
part of
Xenobiotics
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
exact match
https://identifiers.org/reactome:R-HSA-211910
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
has part(s)
hydron
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
NADPH
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
dioxygen
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
paclitaxel
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
water
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
6α-hydroxypaclitaxel
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
NADP+
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
cites work
Human liver microsomal metabolism of paclitaxel and drug interactions
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
Identifiers
Reactome ID
R-HSA-211910
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-211910
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