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Protein Kinase B/Akt phosphorylates BRF1
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-450490)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
part of
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
1 reference
stated in
Reactome
retrieved
13 July 2022
Reactome ID
R-HSA-450490
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
exact match
https://identifiers.org/reactome:R-HSA-450490
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
has part(s)
ATP(4-)
quantity
2
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
BRF1:mRNA Complex [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
ADP(3-)
quantity
2
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
Phosphorylated BRF1 (Ser92, Ser203):mRNA Complex [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
p-T308,S473-AKT1 [cytosol]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
cites work
The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
BRF1 protein turnover and mRNA decay activity are regulated by protein kinase B at the same phosphorylation sites
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
Identifiers
Reactome ID
R-HSA-450490
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450490
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