(Q50295951)

English

GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-6787403)

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8 July 2022

mitochondrial tRNA modification

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8 July 2022

tRNA modification in the mitochondrion

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-6787403

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8 July 2022

tRNA(Leu,Lys) containing U-34 [mitochondrial matrix]

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8 July 2022

tRNA(Lys,Leu) containing 5-taurinomethylU-34 [mitochondrial matrix]

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8 July 2022

GTP binding protein 3, mitochondrial

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8 July 2022

Mitochondrial tRNA translation optimization 1

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8 July 2022

Taurine as a constituent of mitochondrial tRNAs: new insights into the functions of taurine and human mitochondrial diseases

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8 July 2022

Mutations of the mitochondrial-tRNA modifier MTO1 cause hypertrophic cardiomyopathy and lactic acidosis

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8 July 2022

MTO1 mutations are associated with hypertrophic cardiomyopathy and lactic acidosis and cause respiratory chain deficiency in humans and yeast

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8 July 2022

MTO1 mediates tissue specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention

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8 July 2022

Metabolic and chemical regulation of tRNA modification associated with taurine deficiency and human disease.

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q50295951)

GTPBP3 and MTO1 transform uridine-34 yielding 5-taurinomethyluridine-34 in tRNA

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