(Q50297439)

English

Viral serpin blocks caspase-8 activity

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2672196)

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1 reference

8 July 2022

suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 July 2022

CASP8 activity is inhibited

1 reference

8 July 2022

Regulation of TNFR1 signaling

1 reference

8 July 2022

Microbial modulation of RIPK1-mediated regulated necrosis

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-2672196

1 reference

8 July 2022

active caspase-8 [cytosol]

quantity

1

object of statement has role

1 reference

8 July 2022

viral serpins [cytosol]

quantity

1

object of statement has role

1 reference

8 July 2022

active caspase-8:viral CRMA/SPI-2 [cytosol]

quantity

1

object of statement has role

1 reference

8 July 2022

Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product

1 reference

8 July 2022

Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway

1 reference

8 July 2022

Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1beta-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1beta-induced fever

1 reference

8 July 2022

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q50297439)

Viral serpin blocks caspase-8 activity

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