(Q50297509)

English

Sprouty sequesters CBL away from active EGFR

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-182990)

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Statements

biological process

1 reference

8 July 2022

EGFR downregulation

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-182990

1 reference

8 July 2022

EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane]

1

object has role

1 reference

8 July 2022

SPRY1/2 [plasma membrane]

1

object has role

1 reference

8 July 2022

EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:SPRY1/2:Endophilin:Epsin:Eps15L1:EPS15 [plasma membrane]

1

object has role

1 reference

8 July 2022

Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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