(Q50297510)

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PTPN12 dephosphorylates EGFR at Y1148 (Y1172)

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8864029)

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8 July 2022

negative regulation of ERBB signaling pathway

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8 July 2022

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-8864029

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8 July 2022

EGF:p-6Y-EGFR dimer [plasma membrane]

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8 July 2022

EGF:p-EGFR dimer dephosphorylated at Y1148 (Y1172) [plasma membrane]

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8 July 2022

Protein tyrosine phosphatase non-receptor type 12

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8 July 2022

hydrogen phosphate ion

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8 July 2022

Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase

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8 July 2022

The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor

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8 July 2022

The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q50297510)

PTPN12 dephosphorylates EGFR at Y1148 (Y1172)

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