(Q50297553)

English

p-CBL:GRB2 binds p-FRS2:activated FGFR1

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5654673)

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Statements

biological process

1 reference

8 July 2022

Negative regulation of FGFR1 signaling

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5654673

1 reference

8 July 2022

Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane]

1

object of statement has role

1 reference

8 July 2022

p-Y371-CBL:GRB2 [cytosol]

1

object of statement has role

1 reference

8 July 2022

Activated FGFR1:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane]

1

object of statement has role

1 reference

8 July 2022

FRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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