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Activated FGFR3 phosphorylates FRS2
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5654408)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
part of
FRS-mediated FGFR3 signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
exact match
https://identifiers.org/reactome:R-HSA-5654408
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
has part(s)
Activated FGFR3:FRS2 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
ATP(4-)
quantity
6
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
Activated FGFR3:p-FRS2 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
ADP(3-)
quantity
6
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
Activated FGFR3:FRS2 [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
Activated FGFR3:p-8T-FRS2 [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
cites work
A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
Suc1-associated neurotrophic factor target (SNT) protein is a major FGF-stimulated tyrosine phosphorylated 90-kDa protein which binds to the SH2 domain of GRB2
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
Identifiers
Reactome ID
R-HSA-5654408
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5654408
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