(Q50298134)

English

RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8875659)

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Statements

biological process

1 reference

8 July 2022

MET receptor recycling

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-8875659

1 reference

8 July 2022

HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane]

1

object has role

1 reference

8 July 2022

HGF:p-Y1234,Y1235,Y1349,Y1356-MET dimer [plasma membrane]

1

object has role

1 reference

8 July 2022

GGC-RAB4:GTP [recycling endosome membrane]

1

object has role

1 reference

8 July 2022

GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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