(Q50298160)

English

Phosphorylated SMAD2/3 dissociates from TGFBR

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-170850)

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Statements

biological process

1 reference

8 July 2022

TGF-beta receptor signaling activates SMADs

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-170850

1 reference

8 July 2022

TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3 [early endosome membrane]

1

object has role

1 reference

8 July 2022

p-2S-SMAD2,3 [cytosol]

1

object has role

1 reference

8 July 2022

TGFB1:p-TGFBR:ZFYVE9 [early endosome membrane]

1

object has role

1 reference

8 July 2022

Structural basis of heteromeric smad protein assembly in TGF-beta signaling

1 reference

8 July 2022

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

1 reference

8 July 2022

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

1 reference

8 July 2022

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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