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SMAD7:SMURF1 complex is exported to the cytosol
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-178215)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
part of
Downregulation of TGF-beta receptor signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
exact match
https://identifiers.org/reactome:R-HSA-178215
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
has part(s)
SMAD7:SMURF1:XPO1 [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
SMAD7:SMURF1 [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
Exportin 1
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
SMAD7:SMURF1:XPO1 [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
cites work
Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
Identifiers
Reactome ID
R-HSA-178215
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-178215
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