(Q50298795)

English

ZNRF3 ubiquitinates FZD to promote its downregulation

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-4641253)

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Statements

biological process

1 reference

8 July 2022

Regulation of FZD by ubiquitination

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-4641253

1 reference

8 July 2022

N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane]

1

object has role

1 reference

8 July 2022

1

object has role

1 reference

8 July 2022

N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane]

1

object has role

1 reference

8 July 2022

N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane]

1

object has role

1 reference

8 July 2022

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

1 reference

8 July 2022

Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma

1 reference

8 July 2022

Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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