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English
DKK promotes clathrin-dependent internalization of LRP6
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5368586)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5368586
part of
Negative regulation of TCF-dependent signaling by WNT ligand antagonists
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5368586
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5368586
exact match
https://identifiers.org/reactome:R-HSA-5368586
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5368586
has part(s)
KRM:DKK:LRP5/6 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5368586
KRM:DKK:LRP5/6 [early endosome membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5368586
cites work
LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5368586
Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5368586
Identifiers
Reactome ID
R-HSA-5368586
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5368586
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