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English
GLI2 is degraded by the proteasome
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5610757)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
part of
Degradation of GLI2 by the proteasome
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
exact match
https://identifiers.org/reactome:R-HSA-5610757
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
has part(s)
ub-p11S-GLI2:SUFU [ciliary base]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
SUFU negative regulator of hedgehog signaling
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
26S proteasome [cytosol]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
cites work
Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
Identifiers
Reactome ID
R-HSA-5610757
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5610757
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