(Q50299999)

English

HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8877760)

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8 July 2022

RAB GEFs exchange GTP for GDP on RABs

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-8877760

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8 July 2022

RAB32,RAB38:GDP:GDIs,CHMs [cytosol]

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8 July 2022

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8 July 2022

RAB32,RAB38:GTP [melanosome membrane]

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8 July 2022

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8 July 2022

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8 July 2022

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8 July 2022

Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes

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8 July 2022

The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes

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8 July 2022

BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles

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8 July 2022

Melanosome maturation defect in Rab38-deficient retinal pigment epithelium results in instability of immature melanosomes during transient melanogenesis

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8 July 2022

Multiple Types of Guanine Nucleotide Exchange Factors (GEFs) for Rab Small GTPases.

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8 July 2022

Varp interacts with Rab38 and functions as its potential effector

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8 July 2022

Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles

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8 July 2022

BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor

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8 July 2022

Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes

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8 July 2022

Mutation of melanosome protein RAB38 in chocolate mice

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8 July 2022

Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes.

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q50299999)

HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38

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