(Q5420624)

Exonuclease 1

1 reference

5'-3' exonuclease, C-terminal domain superfamily

1 reference

XPG N-terminal domain, protein family

1 reference

XPG-I domain, protein family

1 reference

Exonuclease-1, H3TH domain, protein family

1 reference

XPG conserved site, protein family

1 reference

Helix-hairpin-helix motif, class 2, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

13 November 2019

1 reference

13 November 2019

endonuclease activity

1 reference

8 April 2019

single-stranded DNA 5'-3' exodeoxyribonuclease activity

1 reference

8 April 2019

The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

4 references

8 April 2019

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

5'-3' exonuclease activity

IDA

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

RNA-DNA hybrid ribonuclease activity

ISS

1 reference

8 April 2019

Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

11 references

8 April 2019

HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Human exonuclease I interacts with the mismatch repair protein hMSH2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

The interaction of DNA mismatch repair proteins with human exonuclease I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

A defined human system that supports bidirectional mismatch-provoked excision

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Pathophysiology of ulcer disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Identification of factors interacting with hMSH2 in the fetal liver utilizing the yeast two-hybrid system. In vivo interaction through the C-terminal domains of hEXO1 and hMSH2 and comparative expression analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Functional alterations of human exonuclease 1 mutants identified in atypical hereditary nonpolyposis colorectal cancer syndrome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

DNA end resection by CtIP and exonuclease 1 prevents genomic instability

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

EXD2 promotes homologous recombination by facilitating DNA end resection

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

hydrolase activity, acting on ester bonds

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

5 references

10 September 2018

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

double-stranded DNA binding

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

5'-flap endonuclease activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

single-stranded DNA 5'-3' exodeoxyribonuclease activity

flap endonuclease activity

IDA

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

double-stranded DNA 5'-3' exodeoxyribonuclease activity

3 references

10 September 2018

The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

5'-3' exodeoxyribonuclease activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

1 January 2018

HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

1 January 2018

Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLalpha and hMLH1-hEXO1 complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

immune system process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

humoral immune response mediated by circulating immunoglobulin

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

6 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

24 April 2018

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

24 April 2018

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

24 April 2018

Human exonuclease I interacts with the mismatch repair protein hMSH2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

24 April 2018

Human exonuclease I is required for 5' and 3' mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

24 April 2018

Mechanism of 5'-directed excision in human mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

cellular response to DNA damage stimulus

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

somatic hypermutation of immunoglobulin genes

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

3 references

8 April 2019

Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

RNA phosphodiester bond hydrolysis, endonucleolytic

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

nucleic acid phosphodiester bond hydrolysis

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

1 reference

8 April 2019

A balance between elongation and trimming regulates telomere stability in stem cells

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

meiotic DNA double-strand break processing

TAS

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ84&geneProductId=UniProtKB:Q9UQ84

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Human exonuclease I interacts with the mismatch repair protein hMSH2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Human exonuclease I is required for 5' and 3' mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Mechanism of 5'-directed excision in human mismatch repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

3 references

8 April 2019

Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

regulation of signal transduction by p53 class mediator

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ84

TAS

Gene Atlas image

PBB GE EXO1 204603 at fs.png
732 × 530; 12 KB

0 references

has part(s)

XPG-I domain

1 reference

Helix-hairpin-helix motif, class 2

1 reference

XPG conserved site

1 reference

XPG N-terminal

1 reference

Exonuclease-1, H3TH domain

1 reference