Wikidata

(Q5446439)

English

Fibrillarin

mammalian protein found in Homo sapiens

  • histone-glutamine methyltransferase
  • rRNA 2'-O-methyltransferase fibrillarin
  • 34-kD nucleolar scleroderma antigen
  • FBL
  • RNA, U3 small nucleolar interacting protein 1
  • 34 kDa nucleolar scleroderma antigen
In more languages

Statements

molecular function
protein binding
determination method
IPI
7 references
retrieved
8 April 2019
stated in
NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IPI
retrieved
8 April 2019
stated in
PHF6 interacts with the nucleosome remodeling and deacetylation (NuRD) complex
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IPI
retrieved
8 April 2019
stated in
Human 1A6/DRIM, the homolog of yeast Utp20, functions in the 18S rRNA processing
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IPI
retrieved
8 April 2019
stated in
A dynamic scaffold of pre-snoRNP factors facilitates human box C/D snoRNP assembly
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IPI
retrieved
8 April 2019
stated in
The nuclear DEAD box RNA helicase p68 interacts with the nucleolar protein fibrillarin and colocalizes specifically in nascent nucleoli during telophase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IPI
retrieved
8 April 2019
stated in
RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IPI
retrieved
8 April 2019
stated in
An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IPI
RNA binding
determination method
IBA
IDA
IEA
TAS
6 references
retrieved
31 October 2017
stated in
cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22087&geneProductId=UniProtKB:P22087
determination method
TAS
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22087&geneProductId=UniProtKB:P22087
determination method
IEA
retrieved
31 October 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22087&geneProductId=UniProtKB:P22087
determination method
IEA
retrieved
31 October 2017
stated in
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22087&geneProductId=UniProtKB:P22087
determination method
IDA
retrieved
31 October 2017
stated in
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22087&geneProductId=UniProtKB:P22087
determination method
IDA
retrieved
31 October 2017
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P22087&geneProductId=UniProtKB:P22087
determination method
IBA
RNA binding
determination method
HDA
IBA
IEA
TAS
6 references
retrieved
8 April 2019
stated in
cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IBA
retrieved
8 April 2019
stated in
The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
HDA
retrieved
8 April 2019
stated in
Insights into RNA biology from an atlas of mammalian mRNA-binding proteins
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
HDA
cell component
nucleolus
determination method
IDA
IEA
8 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IEA
retrieved
8 April 2019
stated in
Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IDA
retrieved
8 April 2019
stated in
Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36.
GOA
curator
UniProt
UniProt protein ID
P22087
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IDA
retrieved
8 April 2019
stated in
GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IDA
retrieved
8 April 2019
stated in
Multiple controls regulate nucleostemin partitioning between nucleolus and nucleoplasm
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IDA
retrieved
8 April 2019
stated in
A non-catalytic role for inositol 1,3,4,5,6-pentakisphosphate 2-kinase in the synthesis of ribosomal RNA.
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IDA
retrieved
8 April 2019
stated in
Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22087
determination method
IDA
biological process
Gene Atlas image
PBB GE FBL 211623 s at fs.png
732 × 530; 12 KB
0 references

Identifiers

Ensembl protein ID
 
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