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(Q54931215)
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NYH/187/162
cell line
NYH/187
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Statements
instance of
cell line
1 reference
stated in
Cellosaurus release 44
retrieved
27 January 2023
Cellosaurus ID
CVCL_0B24
cancer cell line
1 reference
stated in
Cellosaurus release 44
retrieved
27 January 2023
Cellosaurus ID
CVCL_0B24
parent cell line
GLC-2
1 reference
stated in
Cellosaurus release 44
retrieved
27 January 2023
Cellosaurus ID
CVCL_0B24
described by source
Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the alpha isoform
1 reference
stated in
Cellosaurus release 44
retrieved
27 January 2023
Cellosaurus ID
CVCL_0B24
Human small cell lung cancer NYH cells resistant to the bisdioxopiperazine ICRF-187 exhibit a functional dominant Tyr165Ser mutation in the Walker A ATP binding site of topoisomerase II alpha.
1 reference
stated in
Cellosaurus release 44
retrieved
27 January 2023
Cellosaurus ID
CVCL_0B24
established from medical condition
lung small cell carcinoma
1 reference
stated in
Cellosaurus release 44
retrieved
27 January 2023
Cellosaurus ID
CVCL_0B24
derived from organism type
Homo sapiens
sex or gender
male
1 reference
stated in
Cellosaurus release 44
retrieved
27 January 2023
Cellosaurus ID
CVCL_0B24
Identifiers
Cellosaurus ID
CVCL_0B24
1 reference
stated in
Cellosaurus release 44
retrieved
27 January 2023
Cellosaurus ID
CVCL_0B24
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