(Q5512833)

Protein kinase-like domain superfamily

1 reference

Protein-tyrosine phosphatase-like

1 reference

Tensin phosphatase, C2 domain, protein family

1 reference

Tensin-type phosphatase domain, protein family

1 reference

DnaJ domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

protein kinase activity

1 reference

8 April 2019

5 references

8 April 2019

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

8 April 2019

Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

8 April 2019

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

8 April 2019

Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

8 April 2019

Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

8 April 2019

The clathrin-binding and J-domains of GAK support the uncoating and chaperoning of clathrin by Hsc70 in the brain

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14976&geneProductId=UniProtKB:O14976

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

26 September 2017

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14976&geneProductId=UniProtKB:O14976

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

8 April 2019

Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

26 September 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14976&geneProductId=UniProtKB:O14976

intracellular membrane-bounded organelle

IDA

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14976&geneProductId=UniProtKB:O14976

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14976&geneProductId=UniProtKB:O14976

1 reference

8 April 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

biological process

protein phosphorylation

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

negative regulation of neuron projection development

1 reference

8 April 2019

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

clathrin-dependent endocytosis

1 reference

26 September 2017

Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14976&geneProductId=UniProtKB:O14976

clathrin coat disassembly

1 reference

26 September 2017

Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14976&geneProductId=UniProtKB:O14976

Golgi to lysosome transport

1 reference

8 April 2019

Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

endoplasmic reticulum organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

synaptic vesicle uncoating

ISS

1 reference

8 April 2019

Endocytosis and clathrin-uncoating defects at synapses of auxilin knockout mice

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

chaperone cofactor-dependent protein refolding

ISS

1 reference

8 April 2019

The clathrin-binding and J-domains of GAK support the uncoating and chaperoning of clathrin by Hsc70 in the brain

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

TAS

membrane organization

1 reference

8 April 2019

clathrin-coated pit assembly

TAS

1 reference

8 April 2019

Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

receptor-mediated endocytosis

1 reference

26 September 2017

Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14976&geneProductId=UniProtKB:O14976

protein localization to plasma membrane

1 reference

8 April 2019

Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

protein localization to Golgi apparatus

1 reference

8 April 2019

Depletion of GAK/auxilin 2 inhibits receptor-mediated endocytosis and recruitment of both clathrin and clathrin adaptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14976

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5269

English

retrieved

17 August 2016

has part(s)

protein kinase domain

1 reference

serine/threonine-protein kinase, active site

1 reference

DnaJ domain

1 reference

Tensin-type phosphatase domain

1 reference

Tensin phosphatase, C2 domain

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016