Wikidata

(Q5512896)

English

GATA binding protein 1

mammalian protein found in Homo sapiens

  • NF-E1 DNA-binding protein
  • GATA1
  • transcription factor GATA1
  • erythroid transcription factor 1
  • GATA-binding factor 1
  • nuclear factor, erythroid 1
  • GF-1
  • GATA-1
  • Eryf1
  • erythroid transcription factor
  • globin transcription factor 1
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No label defined

No description defined

Statements

molecular function
DNA binding
determination method or standard
IEA
IDA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
8 April 2019
stated in
Knockdown of ZNF268, which Is Transcriptionally Downregulated by GATA-1, Promotes Proliferation of K562 Cells
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
8 April 2019
stated in
A novel erythroid differentiation related gene EDRF1 upregulating globin gene expression in HEL cells
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
8 April 2019
stated in
A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
8 April 2019
stated in
Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IDA
protein binding
determination method or standard
IPI
7 references
retrieved
8 April 2019
stated in
Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IPI
retrieved
8 April 2019
stated in
A Novel In-Frame Deletion in the Leucine Zipper Domain of C/EBPε Leads to Neutrophil-Specific Granule Deficiency
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IPI
retrieved
8 April 2019
stated in
CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IPI
retrieved
8 April 2019
stated in
The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IPI
retrieved
8 April 2019
stated in
Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IPI
retrieved
8 April 2019
stated in
Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IPI
cell component
nucleus
determination method or standard
IEA
IDA
6 references
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
5 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
5 June 2018
stated in
Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
5 June 2018
stated in
Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
5 June 2018
stated in
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IDA
nucleus
determination method or standard
IBA
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
8 April 2019
stated in
Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
8 April 2019
stated in
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
8 April 2019
stated in
Increased gamma-globin expression in a nondeletion HPFH mediated by an erythroid-specific DNA-binding factor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15976
determination method or standard
IBA
biological process
platelet formation
determination method or standard
IBA
IEA
IMP
5 references
retrieved
1 January 2018
stated in
Molecular cloning and characterization of the GATA1 cofactor human FOG1 and assessment of its binding to GATA1 proteins carrying D218 substitutions
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IMP
retrieved
1 January 2018
stated in
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IMP
retrieved
1 January 2018
stated in
X-linked thrombocytopenia caused by a novel mutation of GATA-1
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IMP
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IBA
positive regulation of transcription by RNA polymerase II
determination method or standard
IBA
IDA
IEA
IMP
5 references
retrieved
1 January 2018
stated in
Developmental silencing of human zeta-globin gene expression is mediated by the transcriptional repressor RREB1
GOA
curator
UniProt
UniProt protein ID
P15976
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IMP
retrieved
1 January 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IEA
retrieved
1 January 2018
stated in
GATA-1 forms distinct activating and repressive complexes in erythroid cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
1 January 2018
stated in
X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IDA
retrieved
1 January 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P15976&geneProductId=UniProtKB:P15976
determination method or standard
IBA