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English
DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1)
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9023632)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
part of
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
exact match
https://identifiers.org/reactome:R-HSA-9023632
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
has part(s)
mature GLP1 [extracellular region]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
GLP-1 (Cleaved at N-terminus) [extracellular region]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
Dipeptidyl peptidase 4
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
cites work
Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
Investigation of glucose-dependent insulinotropic polypeptide-(1-42) and glucagon-like peptide-1-(7-36) degradation in vitro by dipeptidyl peptidase IV using matrix-assisted laser desorption/ionization-time of flight mass spectrometry. A novel [...]
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
Characterisation of human dipeptidyl peptidase IV expressed in Pichia pastoris. A structural and mechanistic comparison between the recombinant human and the purified porcine enzyme.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
Identifiers
Reactome ID
R-HSA-9023632
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9023632
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