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EGFR phosphorylates NOTCH3
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9018572)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
negative regulation of Notch signaling pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
part of
NOTCH3 Activation and Transmission of Signal to the Nucleus
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
exact match
https://identifiers.org/reactome:R-HSA-9018572
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
has part(s)
ATP(4-)
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
EGF:p-6Y-EGFR dimer:NICD3 [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
ADP(3-)
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
EGF:p-6Y-EGFR dimer [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
p-Y-NICD3 [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
EGF:p-6Y-EGFR dimer:NICD3 [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
cites work
EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
Identifiers
Reactome ID
R-HSA-9018572
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9018572
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