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WWP2 ubiquitinates NOTCH3
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9021523)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
negative regulation of Notch signaling pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
part of
NOTCH3 Activation and Transmission of Signal to the Nucleus
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
exact match
https://identifiers.org/reactome:R-HSA-9021523
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
has part(s)
NEXT3,NICD3:WWP2 [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
Ub [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
Ub-NEXT3,Ub-NICD3:WWP2 [cytosol]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
NEXT3,NICD3:WWP2 [cytosol]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
cites work
Notch3 interactome analysis identified WWP2 as a negative regulator of Notch3 signaling in ovarian cancer
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
Identifiers
Reactome ID
R-HSA-9021523
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9021523
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