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Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9011983)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
part of
Estrogen-dependent gene expression
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
exact match
https://identifiers.org/reactome:R-HSA-9011983
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
has part(s)
ESR1 dimer:ESTG [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
H2A clustered histone 6
quantity
2
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
MYC gene, BCL2 gene: H3K9me2 nucleosome [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
Histone H2A [nucleoplasm]
quantity
2
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
cites work
DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
Novel trans-tail regulation of H2B ubiquitylation and H3K4 methylation by the N terminus of histone H2A.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
Genome-wide mapping and characterization of hypomethylated sites in human tissues and breast cancer cell lines
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
An H2A histone isotype regulates estrogen receptor target genes by mediating enhancer-promoter-3'-UTR interactions in breast cancer cells
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
Identifiers
Reactome ID
R-HSA-9011983
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9011983
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