(Q5773160)

Ureohydrolase domain superfamily

1 reference

Histone deacetylase 5

1 reference

Histone deacetylase, glutamine rich N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

histone deacetylases

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

NAD-dependent histone deacetylase activity (H3-K14 specific)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

1 reference

8 April 2019

protein deacetylase activity

1 reference

8 April 2019

Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

histone deacetylase binding

1 reference

8 April 2019

Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

chromatin binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

1 reference

8 April 2019

protein binding

14 references

8 April 2019

Human BAHD1 promotes heterochromatic gene silencing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

BCoR, a novel corepressor involved in BCL-6 repression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

The functional interactome landscape of the human histone deacetylase family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

An expression screen reveals modulators of class II histone deacetylase phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

1 reference

8 April 2019

protein kinase C binding

1 reference

8 April 2019

Protein kinase C-related kinase targets nuclear localization signals in a subset of class IIa histone deacetylases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

histone deacetylase activity

Three proteins define a class of human histone deacetylases related to yeast Hda1p

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

8 April 2019

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

transcription factor binding

SUMO modification regulates the transcriptional activity of XBP1

3 references

8 April 2019

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

cell component

Golgi apparatus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

1 reference

8 April 2019

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

1 reference

8 April 2019

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

1 reference

8 April 2019

nuclear speck

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

1 reference

8 April 2019

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

biological process

histone H3 deacetylation

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

chromatin remodeling

1 reference

8 April 2019

Three proteins define a class of human histone deacetylases related to yeast Hda1p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

regulation of myotube differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

1 reference

8 April 2019

regulation of transcription, DNA-templated

ISS

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQL6&geneProductId=UniProtKB:Q9UQL6

1 reference

5 June 2018

positive regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

regulation of histone H3-K9 acetylation

1 reference

8 April 2019

Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

response to activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQL6&geneProductId=UniProtKB:Q9UQL6

1 reference

5 June 2018

protein deacetylation

1 reference

8 April 2019

Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

negative regulation of cell migration involved in sprouting angiogenesis

1 reference

8 April 2019

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

B cell activation

1 reference

8 April 2019

Class II histone deacetylases: versatile regulators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

neuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

negative regulation of myotube differentiation

cellular response to insulin stimulus

NAS

1 reference

8 April 2019

AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

NAS

B cell differentiation

1 reference

8 April 2019

Class II histone deacetylases: versatile regulators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

inflammatory response

1 reference

8 April 2019

Class II histone deacetylases: versatile regulators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

regulation of protein binding

1 reference

8 April 2019

Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

Class II histone deacetylases: versatile regulators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

cellular response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Transcriptional activation of hypoxia-inducible factor-1alpha by HDAC4 and HDAC5 involves differential recruitment of p300 and FIH-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

response to cocaine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

negative regulation of transcription by RNA polymerase II

Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

8 April 2019

Class II histone deacetylases confer signal responsiveness to the ankyrin-repeat proteins ANKRA2 and RFXANK.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQL6

chromatin organization

physically interacts with

3 references

1 reference

7496

17 August 2016

1 reference

7490

17 August 2016

1 reference

8365

17 August 2016

1 reference

7503

17 August 2016

1 reference

7006

17 August 2016

1 reference

7005

17 August 2016

1 reference

6852

English

Histone deacetylase domain

17 August 2016

Gene Atlas image

PBB GE HDAC5 202455 at fs.png
732 × 530; 12 KB

0 references

has part(s)

1 reference

Histone deacetylase, glutamine rich N-terminal domain

1 reference