(Q6055408)

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

1 reference

PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily

1 reference

EF-hand domain pair

1 reference

EF-hand domain, protein family

1 reference

C2 domain, protein family

1 reference

Phosphatidylinositol-specific phospholipase C, X domain, protein family

1 reference

Phospholipase C, phosphatidylinositol-specific, Y domain, protein family

1 reference

Phosphoinositide-specific phospholipase C, EF-hand-like domain, protein family

1 reference

phosphoric diester hydrolase activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

signal transducer activity

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

phosphatidylinositol phospholipase C activity

6 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

10 September 2018

Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

10 September 2018

Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

phosphatidylinositol-4,5-bisphosphate binding

IDA

1 reference

8 April 2019

Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

phosphatidylinositol-5-phosphate binding

IDA

1 reference

8 April 2019

Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

phosphatidylinositol-3-phosphate binding

1 reference

8 April 2019

Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

phosphatidylinositol phospholipase C activity

7 references

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

7 November 2018

Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

7 November 2018

Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

phosphatidylinositol-5-phosphate binding

phosphatidylinositol-3-phosphate binding

phosphatidylinositol phospholipase C activity

6 references

8 April 2019

Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLCζ.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

perinuclear region of cytoplasm

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

1 reference

8 April 2019

Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

Difference in Ca2+ oscillation-inducing activity and nuclear translocation ability of PLCZ1, an egg-activating sperm factor candidate, between mouse, rat, human, and medaka fish.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

multicellular organism development

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

lipid catabolic process

1 reference

8 April 2019

intracellular signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

inositol phosphate metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

3 references

8 April 2019

Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

positive regulation of cytosolic calcium ion concentration

positive regulation of cytosolic calcium ion concentration involved in egg activation

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

10 September 2018

Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

10 September 2018

Difference in Ca2+ oscillation-inducing activity and nuclear translocation ability of PLCZ1, an egg-activating sperm factor candidate, between mouse, rat, human, and medaka fish.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q86YW0&geneProductId=UniProtKB:Q86YW0

positive regulation of cytosolic calcium ion concentration involved in egg activation

IDA

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

Difference in Ca2+ oscillation-inducing activity and nuclear translocation ability of PLCZ1, an egg-activating sperm factor candidate, between mouse, rat, human, and medaka fish.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

inositol trisphosphate biosynthetic process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q86YW0

imported from Wikimedia project

EC enzyme number

3.1.4.11

1 reference

Spanish Wikipedia

exact match

http://purl.uniprot.org/uniprot/Q86YW0

1 reference

Phosphatidylinositol-specific phospholipase C, X domain

Identifiers.org

has part(s)

1 reference

EF-hand domain

1 reference

C2 domain

1 reference

Phosphoinositide-specific phospholipase C, EF-hand-like domain

1 reference

Phospholipase C, phosphatidylinositol-specific, Y domain

1 reference