(Q424042)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P18206

Vinculin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P18206

Vinculin, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

31 October 2017

Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

beta-Dystroglycan modulates the interplay between actin and microtubules in human-adhered platelets

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

structural molecule activity

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

17 references

31 October 2017

Vinexin: a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Human alpha-synemin interacts directly with vinculin and metavinculin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Integrin-mediated cell adhesion: the cytoskeletal connection

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

RNA and RNA binding proteins participate in early stages of cell spreading through spreading initiation centers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Structural dynamics of alpha-actinin-vinculin interactions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Structural basis for amplifying vinculin activation by talin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Dimer asymmetry defines α-catenin interactions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Raver1 Interactions with Vinculin and RNA Suggest a Feed-Forward Pathway in Directing mRNA to Focal Adhesions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Capping of actin filaments by vinculin activated by the Shigella IpaA carboxyl-terminal domain

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Vinculin binding in its closed conformation by a helix addition mechanism

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

CAP interacts with cytoskeletal proteins and regulates adhesion-mediated ERK activation and motility

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Role of dystrophins and utrophins in platelet adhesion process

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells

alpha-catenin binding

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

ubiquitin protein ligase binding

1 reference

31 October 2017

Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset

cell component

extracellular vesicle

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

outer dense plaque of desmosome

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

6 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

Complete sequence of human vinculin and assignment of the gene to chromosome 10

IDA

cell-substrate junction

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

inner dense plaque of desmosome

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

3 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

Spatial and temporal expression of the beta1D integrin during mouse development

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

IDA

extracellular exosome

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

IEA

secretory granule lumen

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

specific granule lumen

1 reference

31 October 2017

ficolin-1-rich granule lumen

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

regulation of cell migration

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

adherens junction assembly

1 reference

31 October 2017

Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

epithelial cell-cell adhesion

1 reference

31 October 2017

Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

platelet degranulation

1 reference

31 October 2017

morphogenesis of an epithelium

1 reference

31 October 2017

Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

4 references

31 October 2017

Vinculin--a dynamic regulator of cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

negative regulation of cell migration

IEA

1 reference

31 October 2017

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

protein localization to cell surface

1 reference

31 October 2017

Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

1 reference

31 October 2017

Platelet proteome analysis reveals integrin-dependent aggregation defects in patients with myelodysplastic syndromes.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

alpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cells

apical junction assembly

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

http://www.ebi.ac.uk/QuickGO/annotations?protein=P18206&geneProductId=UniProtKB:P18206

neutrophil degranulation

1 reference

31 October 2017

http://purl.uniprot.org/uniprot/P18206

Gene Atlas image

PBB GE VCL 200931 s at fs.png
732 × 530; 11 KB

0 references

exact match

1 reference

Identifiers.org

has part(s)

Vinculin, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P18206

Identifiers

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016