(Q7202245)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25105

G protein-coupled receptor

1 reference

Transporter Classification Database ID

9.A.14.13.3

hierarchical database ID heuristic

2 October 2019

based on heuristic

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

G protein-coupled receptor activity

The human platelet-activating factor receptor gene (PTAFR) contains no introns and maps to chromosome 1

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

G protein-coupled purinergic nucleotide receptor activity

IBA

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

lipopolysaccharide binding

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

signal transducer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25105&geneProductId=UniProtKB:P25105

1 reference

31 January 2018

mitogen-activated protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

platelet activating factor receptor activity

Chemoattractant receptors activate distinct pathways for chemotaxis and secretion. Role of G-protein usage

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

Molecular cloning and expression of platelet-activating factor receptor from human leukocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

Characterization of a human cDNA that encodes a functional receptor for platelet activating factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

Molecular cloning and characterization of the platelet-activating factor receptor gene expressed in the human heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

phospholipid binding

lipopolysaccharide immune receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

protein binding

IPI

1 reference

8 April 2019

Systematic protein-protein interaction mapping for clinically relevant human GPCRs

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

integral component of membrane

IPI

cell component

Characterization of a human cDNA that encodes a functional receptor for platelet activating factor

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

NAS

8 April 2019

Molecular cloning and characterization of the platelet-activating factor receptor gene expressed in the human heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

The human leukocyte platelet-activating factor receptor. cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

integral component of plasma membrane

1 reference

8 April 2019

Cloning, expression and tissue distribution of rat platelet-activating-factor-receptor cDNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

plasma membrane

secretory granule membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

1 reference

8 April 2019

tertiary granule membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

1 reference

8 April 2019

G protein-coupled receptor signaling pathway

biological process

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25105&geneProductId=UniProtKB:P25105

6 references

31 January 2018

31 January 2018

Chemoattractant receptors activate distinct pathways for chemotaxis and secretion. Role of G-protein usage

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25105&geneProductId=UniProtKB:P25105

31 January 2018

Molecular cloning and expression of platelet-activating factor receptor from human leukocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25105&geneProductId=UniProtKB:P25105

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25105&geneProductId=UniProtKB:P25105

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25105&geneProductId=UniProtKB:P25105

31 January 2018

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25105&geneProductId=UniProtKB:P25105

positive regulation of leukocyte tethering or rolling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

inositol trisphosphate biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of voltage-gated chloride channel activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of phospholipase C activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

negative regulation of blood pressure

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

interferon-gamma-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

1 reference

8 April 2019

positive regulation of inositol phosphate biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of transcytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

cytokine production

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

response to symbiotic bacterium

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

transcytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of translation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

cellular response to gravity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

response to dexamethasone

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of cellular extravasation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of maternal process involved in parturition

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

chemotaxis

Chemoattractant receptors activate distinct pathways for chemotaxis and secretion. Role of G-protein usage

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of sensory perception of pain

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

cellular response to fatty acid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

response to organophosphorus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

birth

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of vasoconstriction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

immune response

1 reference

8 April 2019

Regulation by IL-5 of expression of functional platelet-activating factor receptors on human eosinophils

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of gastro-intestinal system smooth muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of tumor necrosis factor production

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of smooth muscle contraction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of neutrophil degranulation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

positive regulation of leukocyte cell-cell adhesion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

phosphatidylinositol-mediated signaling

1 reference

8 April 2019

Molecular cloning and expression of platelet-activating factor receptor from human leukocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

lipopolysaccharide-mediated signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

cellular response to cAMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

1 reference

8 April 2019

positive regulation of smooth muscle cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

G protein-coupled purinergic nucleotide receptor signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

neutrophil degranulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

1 reference

8 April 2019

cytokine-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

1 reference

8 April 2019

G protein-coupled receptor signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

7 references

8 April 2019

8 April 2019

Chemoattractant receptors activate distinct pathways for chemotaxis and secretion. Role of G-protein usage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

Molecular cloning and expression of platelet-activating factor receptor from human leukocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25105

physically interacts with

IBA

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

1831

language of work or name

English

GPCR, rhodopsin-like, 7TM

17 August 2016

Gene Atlas image

PBB GE PTAFR 206278 at fs.png
732 × 530; 11 KB

0 references

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25105

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

13 January 2016

http://www.uniprot.org/uniprot/P25105.txt?version=155

Transporter Classification Database ID

9.A.14.13.3

2 references

Transporter Classification database

13 March 2020

Transporter Classification database