(Q7275753)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60895

RAMP domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O60895

1 reference

13 November 2019

1 reference

13 November 2019

2 references

3 references

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Involvement of vascular endothelial growth factor signaling in CLR/RAMP1 and CLR/RAMP2-mediated pro-angiogenic effect of intermedin on human vascular endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

adrenomedullin receptor activity

IPI

3 references

9 May 2019

Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

amylin receptor activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding

IGI

adrenomedullin binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

1 reference

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

1 reference

3 January 2017

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

integral component of plasma membrane

1 reference

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

1 reference

3 January 2017

Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

1 reference

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

1 reference

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

amylin receptor complex 2

TAS

1 reference

9 May 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

adrenomedullin receptor complex

4 references

9 May 2019

Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

G protein-coupled receptor signaling pathway

biological process

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

response to estradiol

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

regulation of G protein-coupled receptor signaling pathway

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

response to progesterone

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

receptor internalization

4 references

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

3 January 2017

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

3 January 2017

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

3 January 2017

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

1 reference

9 May 2019

Gene silencing of human RAMP2 mediated by short-interfering RNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

cellular response to hormone stimulus

IMP

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

positive regulation of vasculogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

1 reference

3 January 2017

Involvement of vascular endothelial growth factor signaling in CLR/RAMP1 and CLR/RAMP2-mediated pro-angiogenic effect of intermedin on human vascular endothelial cells

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

intracellular protein transport

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

protein localization to plasma membrane

1 reference

3 January 2017

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

calcium ion transport

1 reference

3 January 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

cAMP biosynthetic process

1 reference

3 January 2017

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O60895

G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

5 references

9 May 2019

Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

3 references

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

receptor internalization

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

protein localization to plasma membrane

amylin receptor signaling pathway

1 reference

9 May 2019

Amyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

adrenomedullin receptor signaling pathway

IGI

4 references

9 May 2019

Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

9 May 2019

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60895

physically interacts with

IPI

1 reference

Open Targets Platform

retrieved

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2103758

Identifiers

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

21 March 2016

1 reference

21 March 2016

1 reference

21 March 2016

1 reference

21 March 2016

Transporter Classification Database ID

English

8.A.127.1.2

2 references

Transporter Classification database

retrieved

13 March 2020

Transporter Classification database

29 April 2020

1 reference

inferred by common MeSH mappings on source and on Wikidata