(Q7423594)

English

Sarcolipin

mammalian protein found in Homo sapiens

sarcolipin
SLN

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O00631

Phospholamban (Ca2+-channel and Ca2+-ATPase Regulator)

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method

1 reference

8 April 2019

Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

enzyme inhibitor activity

determination method

1 reference

8 April 2019

Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

enzyme regulator activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

protein binding

determination method

1 reference

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

endoplasmic reticulum membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

determination method

2 references

endoplasmic reticulum

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

biological process

positive regulation of protein depolymerization

determination method

1 reference

8 April 2019

Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

negative regulation of protein-containing complex disassembly

determination method

1 reference

8 April 2019

Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

negative regulation of calcium ion binding

determination method

1 reference

8 April 2019

Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

regulation of calcium ion transport

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

negative regulation of catalytic activity

determination method

1 reference

8 April 2019

Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

negative regulation of calcium ion transmembrane transporter activity

determination method

1 reference

8 April 2019

Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

calcium ion transport

determination method

1 reference

8 April 2019

Characterization of the gene encoding human sarcolipin (SLN), a proteolipid associated with SERCA1: absence of structural mutations in five patients with Brody disease

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

negative regulation of calcium ion import

determination method

1 reference

8 April 2019

Sarcolipin inhibits polymerization of phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

sarcoplasmic reticulum calcium ion transport

determination method

regulation of relaxation of muscle

determination method

sarcoplasmic reticulum calcium ion transport

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

positive regulation of cold-induced thermogenesis

determination method

1 reference

8 April 2019

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

regulation of relaxation of muscle

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

regulation of ATPase-coupled calcium transmembrane transporter activity

determination method

1 reference

8 April 2019

Structure and orientation of sarcolipin in lipid environments

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00631

determination method

Gene Atlas image

PBB GE SLN 205374 at fs.png
732 × 530; 8 KB

0 references

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000304707

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000304707

ENSP00000434189

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000434189

ENSP00000435380

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000435380

PDB structure ID

1 reference

UniProt protein ID

21 March 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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