(Q7684469)

Chaperones and folding of MHC class I molecules in the endoplasmic reticulum

unfolded protein binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

ABC-type peptide antigen transporter activity

1 reference

9 May 2019

Cloning and functional characterization of a subunit of the transporter associated with antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

10 references

9 May 2019

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

The binding of TAPBPR and Tapasin to MHC class I is mutually exclusive

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

MHC class I protein binding

IPI

1 reference

9 May 2019

Chaperones and folding of MHC class I molecules in the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

1 reference

9 May 2019

Molecular architecture of the TAP-associated MHC class I peptide-loading complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

1 reference

9 May 2019

Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex (MHC) class I molecules from the Golgi complex to the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

1 reference

27 March 2018

Molecular architecture of the TAP-associated MHC class I peptide-loading complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15533&geneProductId=UniProtKB:O15533

MHC class I peptide loading complex

IDA

1 reference

27 March 2018

Chaperones and folding of MHC class I molecules in the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15533&geneProductId=UniProtKB:O15533

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

NAS

endoplasmic reticulum

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

Cloning and functional characterization of a subunit of the transporter associated with antigen processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

integral component of lumenal side of endoplasmic reticulum membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

phagocytic vesicle membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

endoplasmic reticulum-Golgi intermediate compartment membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

MHC class I peptide loading complex

3 references

9 May 2019

Chaperones and folding of MHC class I molecules in the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

Distinct functions for the glycans of tapasin and heavy chains in the assembly of MHC class I molecules.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

9 May 2019

Molecular architecture of the TAP-associated MHC class I peptide-loading complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

IDA

biological process

1 reference

9 May 2019

Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex (MHC) class I molecules from the Golgi complex to the endoplasmic reticulum

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

antigen processing and presentation of peptide antigen via MHC class I

NAS

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

antigen processing and presentation of endogenous peptide antigen via MHC class I

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

regulation of protein complex stability

1 reference

9 May 2019

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

1 reference

9 May 2019

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

peptide antigen stabilization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

regulation of gene expression

ISS

1 reference

9 May 2019

The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

IMP

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

protein-containing complex assembly

1 reference

27 March 2018

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

http://www.ebi.ac.uk/QuickGO/annotations?protein=O15533&geneProductId=UniProtKB:O15533

MHC class Ib protein complex assembly

1 reference

9 May 2019

An essential function of tapasin in quality control of HLA-G molecules

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533

Gene Atlas image

PBB GE TAPBP 210294 at fs.png
732 × 530; 12 KB

0 references

has part(s)

immunoglobulin C1-set

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O15533

immunoglobulin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O15533

Identifiers

1 reference

30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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13 November 2019

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9 August 2016

language of work or name

English

Transporter Classification Database ID

9.A.75.1.2

2 references

Transporter Classification database

retrieved

13 March 2020