(Q7701617)

Cryptic/Cripto, CFC domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

The CRIPTO/FRL-1/CRYPTIC (CFC) domain of human Cripto. Functional and structural insights through disulfide structure analysis

GOA

curator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

IPI

growth factor activity

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

8 April 2019

Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

8 April 2019

Identification and biological characterization of an epidermal growth factor-related protein: cripto-1

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

signaling receptor binding

1 reference

31 January 2018

Cripto-1 activates nodal- and ALK4-dependent and -independent signaling pathways in mammary epithelial Cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13385&geneProductId=UniProtKB:P13385

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

activin receptor binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

2 references

1 reference

31 January 2018

Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13385&geneProductId=UniProtKB:P13385

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

apical plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

anchored component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

extrinsic component of plasma membrane

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13385&geneProductId=UniProtKB:P13385

1 reference

8 April 2019

Cripto: a tumor growth factor and more

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

cellular response to interleukin-6

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

epidermal growth factor receptor signaling pathway

1 reference

8 April 2019

Identification and biological characterization of an epidermal growth factor-related protein: cripto-1

GOA

curator

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

somatic stem cell population maintenance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

positive regulation of cell migration

1 reference

8 April 2019

A Nodal- and ALK4-independent signaling pathway activated by Cripto-1 through Glypican-1 and c-Src

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

cellular response to hepatocyte growth factor stimulus

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

cellular response to tumor necrosis factor

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

negative regulation of apoptotic process

1 reference

8 April 2019

Cripto-1 induces phosphatidylinositol 3'-kinase-dependent phosphorylation of AKT and glycogen synthase kinase 3beta in human cervical carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

cellular response to fibroblast growth factor stimulus

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

morphogenesis of a branching structure

1 reference

8 April 2019

Cripto: a novel epidermal growth factor (EGF)-related peptide in mammary gland development and neoplasia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

cell migration involved in sprouting angiogenesis

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

mammary gland development

IMP

1 reference

8 April 2019

Cripto: a tumor growth factor and more

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

positive regulation of endothelial cell migration

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

cellular response to epidermal growth factor stimulus

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

1 reference

31 January 2018

Specific arrest of cardiogenesis in cultured embryonic stem cells lacking Cripto-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13385&geneProductId=UniProtKB:P13385

regulation of signal transduction

1 reference

8 April 2019

A Nodal- and ALK4-independent signaling pathway activated by Cripto-1 through Glypican-1 and c-Src

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

peptidyl-serine phosphorylation

1 reference

8 April 2019

Cripto-1 induces phosphatidylinositol 3'-kinase-dependent phosphorylation of AKT and glycogen synthase kinase 3beta in human cervical carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

Cripto-1 induces phosphatidylinositol 3'-kinase-dependent phosphorylation of AKT and glycogen synthase kinase 3beta in human cervical carcinoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

cellular response to interferon-gamma

1 reference

8 April 2019

Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

anterior/posterior axis specification, embryo

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

regulation of signaling receptor activity

ISS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

embryo development ending in birth or egg hatching

IEA

1 reference

8 April 2019

Cripto: a tumor growth factor and more

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

determination of left/right symmetry

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

anterior/posterior pattern specification

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

BMP signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

nodal signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

anatomical structure development

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13385

Gene Atlas image

PBB GE TDGF1 206286 s at fs.png
732 × 530; 12 KB

0 references

has part(s)

EGF-like domain

1 reference

Cryptic/Cripto, CFC domain

1 reference

EGF-like, conserved site

1 reference