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Urotensin 2 receptor
mammalian protein found in Homo sapiens
UTS2R
UR-II-R
urotensin-2 receptor
urotensin II receptor
G-protein coupled receptor 14
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UKP6
part of
Urotensin II receptor
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UKP6
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UKP6
encoded by
UTS2R
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UKP6
molecular function
G protein-coupled receptor activity
determination method
TAS
IEA
3 references
retrieved
8 April 2019
stated in
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UKP6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
signal transducer activity
determination method
IEA
1 reference
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UKP6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
urotensin II receptor activity
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IBA
G protein-coupled peptide receptor activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IBA
cell component
integral component of membrane
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UKP6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
recycling endosome
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
membrane
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UKP6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
plasma membrane
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UKP6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
integral component of plasma membrane
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IBA
early endosome
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
biological process
negative regulation of urine volume
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
negative regulation of blood pressure
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
positive regulation of fibroblast proliferation
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
positive regulation of cytosolic calcium ion concentration
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
blood circulation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
TAS
positive regulation of angiogenesis
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
regulation of blood pressure
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
phospholipase C-activating G protein-coupled receptor signaling pathway
determination method
IBA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IBA
positive regulation of blood pressure
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
positive regulation of cell growth
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
positive regulation of vasoconstriction
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
positive regulation of circadian sleep/wake cycle, wakefulness
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
positive regulation of circadian sleep/wake cycle, REM sleep
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
negative regulation of renal sodium excretion
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
neuropeptide signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IBA
negative regulation of glomerular filtration
determination method
IEA
1 reference
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UKP6&geneProductId=UniProtKB:Q9UKP6
determination method
IEA
signal transduction
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UKP6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
blood vessel diameter maintenance
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
G protein-coupled receptor signaling pathway
determination method
IEA
TAS
3 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9UKP6
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UKP6
determination method
IEA
physically interacts with
palosuran
object has role
antagonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL567303
has part(s)
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9UKP6
Identifiers
RefSeq protein ID
NP_061822
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2837
NP_001368826
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2837
UniProt protein ID
Q9UKP6
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
Q9UKP6
Ensembl protein ID
ENSP00000323516
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000323516
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