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(Q7953600)
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Cellular communication network factor 5
mammalian protein found in Homo sapiens
CTGF-L
connective tissue growth factor-related protein 58
connective tissue growth factor-like protein
WISP2
WNT1 inducible signaling pathway protein 2
CCN family member 5
CCN5
WNT1-inducible-signaling pathway protein 2
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O76076
part of
Thrombospondin type-1 (TSP1) repeat superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O76076
Growth factor receptor cysteine-rich domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O76076
VWFC domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Insulin-like growth factor-binding protein, IGFBP family
1 reference
based on heuristic
inferred from protein domain or family
Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
Thrombospondin type-1 (TSP1) repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O76076
encoded by
CCN5
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O76076
molecular function
insulin-like growth factor binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IEA
integrin binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IBA
heparin binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IBA
cell component
extracellular region
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O76076
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IEA
extracellular space
determination method
IDA
2 references
retrieved
8 April 2019
stated in
Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functions
GOA
curator
UniProt
UniProt protein ID
O76076
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IDA
retrieved
8 April 2019
stated in
WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.
GOA
curator
UniProt
UniProt protein ID
O76076
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IDA
extracellular matrix
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IBA
nucleus
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
CCN5, a secreted protein, localizes to the nucleus
GOA
curator
UniProt
UniProt protein ID
O76076
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IDA
biological process
cell-cell signaling
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
TAS
regulation of cell growth
determination method
IEA
1 reference
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O76076&geneProductId=UniProtKB:O76076
determination method
IEA
signal transduction
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
TAS
cell adhesion
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O76076
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IBA
negative regulation of cell death
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76076
determination method
IBA
Gene Atlas image
PBB GE WISP2 205792 at fs.png
732 × 530; 10 KB
0 references
exact match
https://identifiers.org/uniprot:O76076
1 reference
stated in
Identifiers.org
UniProt protein ID
O76076
reference URL
https://registry.identifiers.org/registry/uniprot
http://purl.uniprot.org/uniprot/O76076
1 reference
stated in
Identifiers.org
UniProt protein ID
O76076
reference URL
https://registry.identifiers.org/registry/uniprot
https://www.ncbi.nlm.nih.gov/protein/O76076
1 reference
stated in
Identifiers.org
UniProt protein ID
O76076
reference URL
https://registry.identifiers.org/registry/uniprot
has part(s)
VWFC domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O76076
Thrombospondin type-1 (TSP1) repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O76076
Insulin-like growth factor-binding protein, IGFBP
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O76076
Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O76076
Identifiers
RefSeq protein ID
NP_001310298
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
8839
NP_001310299
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
8839
NP_003872
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
8839
XP_016883605
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
8839
XP_016883606
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
8839
UniProt protein ID
O76076
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O76076
Ensembl protein ID
ENSP00000190983
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000190983
ENSP00000361956
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000361956
ENSP00000361959
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000361959
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