(Q798252)

English

Apolipoprotein D

mammalian protein found in Homo sapiens

apo-D
apolipoprotein D
APOD

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05090

Apolipoprotein D, vertebrates

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05090

Lipocalin/cytosolic fatty-acid binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Lipocalin family conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

lipid transporter activity

determination method

1 reference

8 April 2019

Cloning and expression of human apolipoprotein D cDNA

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

transporter activity

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

cholesterol binding

determination method

1 reference

17 October 2017

Probing the structure of the ligand binding cavity of lipocalins by fluorescence spectroscopy

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

protein binding

determination method

3 references

8 April 2019

Structure of human apolipoprotein D: locations of the intermolecular and intramolecular disulfide links

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

small molecule binding

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

cytosolic ribosome

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

intracellular anatomical structure

determination method

1 reference

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

neuronal cell body

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

endoplasmic reticulum

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

perinuclear region of cytoplasm

determination method

1 reference

8 April 2019

Apolipoprotein D inhibits platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferated by preventing translocation of phosphorylated extracellular signal regulated kinase 1/2 to the nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

extracellular exosome

determination method

3 references

17 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

17 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

extracellular space

determination method

3 references

17 October 2017

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

17 October 2017

Endothelial cells downregulate apolipoprotein D expression in mural cells through paracrine secretion and Notch signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

17 October 2017

Proteomics characterization of extracellular space components in the human aorta

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

extracellular region

determination method

3 references

17 October 2017

The human plasma proteome: a nonredundant list developed by combination of four separate sources

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

17 October 2017

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

extracellular region

determination method

3 references

8 April 2019

The human plasma proteome: a nonredundant list developed by combination of four separate sources

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

8 April 2019

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

extracellular space

determination method

3 references

8 April 2019

Endothelial cells downregulate apolipoprotein D expression in mural cells through paracrine secretion and Notch signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

8 April 2019

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

8 April 2019

Proteomics characterization of extracellular space components in the human aorta

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

biological process

negative regulation of T cell migration

determination method

1 reference

8 April 2019

Neuroprotective effect of apolipoprotein D against human coronavirus OC43-induced encephalitis in mice

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

negative regulation of platelet-derived growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

Apolipoprotein D inhibits platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferated by preventing translocation of phosphorylated extracellular signal regulated kinase 1/2 to the nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

negative regulation of monocyte chemotactic protein-1 production

determination method

1 reference

8 April 2019

Neuroprotective effect of apolipoprotein D against human coronavirus OC43-induced encephalitis in mice

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

negative regulation of smooth muscle cell proliferation

determination method

1 reference

8 April 2019

Apolipoprotein D inhibits platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferated by preventing translocation of phosphorylated extracellular signal regulated kinase 1/2 to the nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

tissue regeneration

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

lipid metabolism

determination method

1 reference

17 October 2017

Human apolipoprotein D overexpression in transgenic mice induces insulin resistance and alters lipid metabolism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

negative regulation of smooth muscle cell-matrix adhesion

determination method

1 reference

8 April 2019

Endothelial cells downregulate apolipoprotein D expression in mural cells through paracrine secretion and Notch signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

determination method

1 reference

17 October 2017

Apolipoprotein D: an overview of its role in aging and age-related diseases

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P05090&geneProductId=UniProtKB:P05090

determination method

brain development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

peripheral nervous system axon regeneration

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

response to axon injury

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

determination method

1 reference

8 April 2019

Endothelial cells downregulate apolipoprotein D expression in mural cells through paracrine secretion and Notch signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

glucose metabolic process

determination method

1 reference

8 April 2019

Human apolipoprotein D overexpression in transgenic mice induces insulin resistance and alters lipid metabolism

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

negative regulation of focal adhesion assembly

determination method

1 reference

8 April 2019

Endothelial cells downregulate apolipoprotein D expression in mural cells through paracrine secretion and Notch signaling

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

negative regulation of protein import into nucleus

determination method

1 reference

8 April 2019

Apolipoprotein D inhibits platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferated by preventing translocation of phosphorylated extracellular signal regulated kinase 1/2 to the nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

negative regulation of cytokine production involved in inflammatory response

determination method

1 reference

8 April 2019

Neuroprotective effect of apolipoprotein D against human coronavirus OC43-induced encephalitis in mice

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

lipid transport

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

response to reactive oxygen species

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

8 April 2019

Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05090

determination method

Gene Atlas image

PBB GE APOD 201525 at fs.png
732 × 530; 10 KB

0 references

http://purl.uniprot.org/uniprot/P05090

1 reference

Identifiers.org

Lipocalin family conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05090

Lipocalin/cytosolic fatty-acid binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05090

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000345179

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000345179

ENSP00000391597

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000391597

ENSP00000393076

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000393076

ENSP00000415235

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000415235

1 reference

Freebase Data Dumps

publication date

28 October 2013

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

ScienceDirect topic ID

agricultural-and-biological-sciences/apolipoprotein-d

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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