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PRPS1 PRPS1 MUTATION
genetic variant
PRPS1 MUTATION
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Statements
biological variant of
PRPS1
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/2916
negative prognostic predictor for
B-cell childhood acute lymphoblastic leukemia
determination method
CIViC evidence level B
rating
CIViC 4-star trust rating
1 reference
curator
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/7871
stated in
Negative feedback-defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL.
Identifiers
CIViC variant ID
2916
1 reference
stated in
CIViC database
retrieved
28 March 2022
reference URL
https://civic.genome.wustl.edu/links/variants/2916
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