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GRB2:SOS1 binds to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9665409)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9665409
part of
Signaling by ERBB2 ECD mutants
1 reference
stated in
Reactome
retrieved
13 July 2022
Reactome ID
R-HSA-9665409
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9665409
exact match
https://identifiers.org/reactome:R-HSA-9665409
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9665409
has part(s)
GRB2-1:SOS1 [cytosol]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9665409
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9665409
p-6Y-ERBB2 ECD mutants:EGF:p-6Y-EGFR:GRB2:SOS1 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9665409
cites work
Activating HER2 mutations in HER2 gene amplification negative breast cancer
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9665409
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9665409
Identifiers
Reactome ID
R-HSA-9665409
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-9665409
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