(Q100152411)

English

Phosphorylated heterodimers of ERBB2 TMD/JMD mutants recruit GRB2:SOS1 through SHC1

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-9665699)

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biological process

1 reference

8 July 2022

Signaling by ERBB2 TMD/JMD mutants

1 reference

13 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-9665699

1 reference

8 July 2022

GRB2-1:SOS1 [cytosol]

1

object of statement has role

1 reference

8 July 2022

p-6Y-ERBB2 TMD/JMD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):p-SHC1 [plasma membrane]

1

object of statement has role

1 reference

8 July 2022

p-6Y-ERBB2 TMD/JMD mutants:Ligand-Activated p-EGFR,p-ERBB3,(p-ERBB4):p-SHC1:GRB2:SOS1 [plasma membrane]

1

object of statement has role

1 reference

8 July 2022

Activating HER2 mutations in HER2 gene amplification negative breast cancer

1 reference

8 July 2022

Impact of ERBB2 mutations on in vitro sensitivity of bladder cancer to lapatinib

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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